A printing plate for computer-to plate lithography having a laser-ablatable member supported by a substrate. At least one portion of the laser-ablatable member is formed form an acrylic polymer containing laser-sensitive particles. The laser-sensitive particles absorb imaging radiation and cause the portion of the laser-ablatable member containing the laser sensitive particles and any overlying layers to be ablated. Alternatively, the printing plate may include a printing member with an initial affinity for a printing fluid that changes to another affinity to printing fluid upon treatment with radiation.